Endosialin/TEM 1/CD248 is a pericyte marker of embryonic and tumor neovascularization
RG Bagley, N Honma, W Weber, P Boutin… - Microvascular …, 2008 - Elsevier
The formation of functional, mature blood vessels depends on the interaction between
endothelial cells and pericytes. Commonality exists in the processes involved in vasculature
development between tissues whether healthy or diseased. Endosialin/TEM 1 is a cell
membrane protein that is expressed in blood vessels during embryogenesis and
tumorigenesis but not in normal mature vessels. Antibodies developed to human endosialin
were used to investigate endosialin expression and function in human prenatal brain …
endothelial cells and pericytes. Commonality exists in the processes involved in vasculature
development between tissues whether healthy or diseased. Endosialin/TEM 1 is a cell
membrane protein that is expressed in blood vessels during embryogenesis and
tumorigenesis but not in normal mature vessels. Antibodies developed to human endosialin
were used to investigate endosialin expression and function in human prenatal brain …
