Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride
BACKGROUND & AIMS: Fibroblast growth factor 21 (FGF21), a hormone primarily secreted
by the liver in response to peroxisome proliferator-activated receptor-α (PPARα) activation,
has recently been shown to possess beneficial effects on lipid metabolism and hepatic
steatosis in animal models. This study investigated the association of FGF21 with
nonalcoholic fatty liver disease (NAFLD) in Chinese patients. METHODS: Serum FGF21
levels were determined by enzyme-linked immunosorbent assay (ELISA) in 224 NAFLD and …
by the liver in response to peroxisome proliferator-activated receptor-α (PPARα) activation,
has recently been shown to possess beneficial effects on lipid metabolism and hepatic
steatosis in animal models. This study investigated the association of FGF21 with
nonalcoholic fatty liver disease (NAFLD) in Chinese patients. METHODS: Serum FGF21
levels were determined by enzyme-linked immunosorbent assay (ELISA) in 224 NAFLD and …
