Multiple sclerosis: mechanisms of disease and strategies for myelin and axonal repair

HN Lemus, AE Warrington… - Neurologic …, 2018 - neurologic.theclinics.com
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) with a variety of clinical presentations. The profound heterogeneity of MS is
not limited to the symptoms but to neuroradiologic and histologic appearances of lesions
and response to therapy. 1 As expected, the pathogenesis of MS is controversial, and there
is no effective treatment that halts the neuro-axonal damage